Accession	MF_01810
Dates	17-NOV-2003 (Created) 30-JUN-2008 (Last updated, Version 21)

Data class

Protein

Predictors

HAMAP; MF_01810; [distribution of match scores in UniProtKB];[seed alignment for MF_01810]

Identifier

OXAA

Protein name

RecName: Full=Membrane protein oxaA;

Protein name

RecName: Full=Inner membrane protein oxaA;

Gene name

oxaA

FUNCTION: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and independently of the Sec translocase complex (By similarity).

SUBUNIT: Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration (By similarity).

SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (By similarity).

SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein (By similarity).

SIMILARITY: Belongs to the OXA1/oxaA family. Type 1 subfamily.

Pfam	PF02096; 60KD_IMP; 1;
PRINTS	PR00701; 60KDINNERMP; 1;
General	Transmembrane; -; 2-7; trigger=Yes;

Membrane, Transmembrane, Cell membrane.

Cell inner membrane.

GO:0005886; Cellular component: plasma membrane.

Size range:	310-795 amino acids
Related UniRules:	MF_01811 (OXAA (supersedes the current rule))
Template:	P25714 (OXAA_ECOLI)
Scope:	Bacteria
Fusion:	Nter: <PDZ/DHR>; Cter: None
Duplicate:	None
Plasmid encoded:	None
Comments:	N-terminal PDZ/DHR fused in RHOBA. In most Firmicutes (MF_01811), this protein is much shorter and contains a signal peptide with a site for a lipid attachment in the N-terminus part.