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HAMAP annotation rule: MF_01657

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General rule information

Accession MF_01657
Dates 5-MAY-2008 (Created)
7-JUN-2008 (Last updated, Version 5)
Data class Protein
Predictors HAMAP; MF_01657; [distribution of match scores in UniProtKB];[seed alignment for MF_01657]


Propagated annotation

Identifier, protein and gene names
Identifier MHPF
Protein name
RecName: Full=Acetaldehyde dehydrogenase;
EC=1.2.1.10;
AltName: Full=Acetaldehyde dehydrogenase [acetylating];
Gene name mhpF
Comments
FUNCTION: Catalyzes the terminal reaction in meta-cleavage pathways, that is, the transformation of acetaldehyde into acetyl coenzyme A (By similarity).
CATALYTIC ACTIVITY: Acetaldehyde + CoA + NAD(+) = acetyl-CoA + NADH.
PATHWAY: Aromatic compound metabolism; 3-phenylpropionic acid degradation.

case <OC:Enterobacteriaceae>
SUBUNIT: Interacts with mhpE (By similarity).
end case

SIMILARITY: Belongs to the acetaldehyde dehydrogenase family. MhpF subfamily.
Cross-references
Pfam PF09290; AcetDehyd-dimer; 1;
PF01118; Semialdhyde_dh; 1;
TIGRFAMs TIGR03215; ac_ald_DH_ac; 1;
Keywords
Aromatic hydrocarbons catabolism, NAD, Oxidoreductase.
Gene Ontology
GO:0008774; Molecular function: acetaldehyde dehydrogenase (acetylating) activity.
GO:0019439; Biological process: aromatic compound catabolic process.


Additional information

Size range: 312-316 amino acids
Related UniRules: None
Template: P77580 (MHPF_ECOLI)
Scope: Bacteria; Proteobacteria
Fusion: Nter: None; Cter: None
Duplicate: None
Plasmid encoded: None

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UniProtKB rule member sequences



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