Accession	MF_01649
Dates	17-APR-2008 (Created) 7-JUN-2008 (Last updated, Version 5)

Data class

Protein

Predictors

HAMAP; MF_01649; [distribution of match scores in UniProtKB];[seed alignment for MF_01649]

Identifier

HCAF

Protein name

RecName: Full=3-phenylpropionate/cinnamic acid dioxygenase subunit beta; EC=1.14.12.19; AltName: Full=Digoxigenin subunit beta;

Gene name

hcaF

FUNCTION: Part of the multicomponent 3-phenylpropionate dioxygenase. Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively (By similarity).

CATALYTIC ACTIVITY: 3-phenylpropanoic acid + NADH + O(2) = cis-3-(2-carboxyethyl)-3,5-cyclohexadiene-1,2-diol + NAD(+).

CATALYTIC ACTIVITY: Cinnamic acid + H(+) + NADH + O(2) = cis-3-(2-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol + NAD(+).

PATHWAY: Aromatic compound metabolism; 3-phenylpropionic acid degradation.

SUBUNIT: This dioxygenase system consists of four proteins: the two subunits of the hydroxylase component (hcaE and hcaF), a ferredoxin (hcaC) and a ferredoxin reductase (hcaD) (By similarity).

SIMILARITY: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

Pfam	PF00866; Ring_hydroxyl_B; 1;

Aromatic hydrocarbons catabolism, Dioxygenase, NAD, Oxidoreductase.

GO:0008695; Molecular function: 3-phenylpropionate dioxygenase activity.
GO:0019439; Biological process: aromatic compound catabolic process.

Size range:	172-180 amino acids
Related UniRules:	None
Template:	Q47140 (HCAF_ECOLI)
Scope:	Bacteria; Enterobacteriaceae
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None