Accession	MF_01645
Dates	14-JAN-2008 (Created) 4-DEC-2008 (Last updated, Version 10)

Data class

Protein

Predictors

HAMAP; MF_01645; [distribution of match scores in UniProtKB];[seed alignment for MF_01645]

Identifier

ALLB

Protein name

RecName: Full=Allantoinase; EC=3.5.2.5; AltName: Full=Allantoin-utilizing enzyme;

Gene name

allB, pucH

Gene name

allB

FUNCTION: Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring (By similarity).

CATALYTIC ACTIVITY: (S)-allantoin + H(2)O = allantoate.

COFACTOR: Binds 2 zinc ions per subunit (By similarity).

PATHWAY: Nitrogen metabolism; (S)-allantoin degradation; allantoate from (S)-allantoin: step 1/1.

SUBUNIT: Homotetramer (By similarity).

PTM: Carbamylation allows a single lysine to coordinate two zinc ions (By similarity).

SIMILARITY: Belongs to the DHOase family. Allantoinase subfamily.

Pfam	PF01979; Amidohydro_1; 1;
TIGRFAMs	TIGR00857; pyrC_multi; 1;

Hydrolase, Metal-binding, Purine metabolism, Zinc.

GO:0004038; Molecular function: allantoinase activity.
GO:0000256; Biological process: allantoin catabolic process.

From: ALLB_ECOLI (P77671)
Key		From		To		Description		Condition		FTGroup
METAL		59		59		Zinc 1 (By similarity)		H
METAL		61		61		Zinc 1 (By similarity)		H
METAL		146		146		Zinc 1; via carbamate group (By similarity)		K
METAL		146		146		Zinc 2; via carbamate group (By similarity)		K
METAL		186		186		Zinc 2 (By similarity)		H
METAL		242		242		Zinc 2 (By similarity)		H
METAL		315		315		Zinc 1 (By similarity)		D
MOD_RES		146		146		N6-carboxylysine (By similarity)		K

Size range:	438-457 amino acids
Related UniRules:	None
Template:	P77671 (ALLB_ECOLI); O32137 (ALLB_BACSU): [Recover all]
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	in DEIGD