Accession	MF_01559
Dates	13-DEC-2005 (Created) 7-JUN-2008 (Last updated, Version 9)

Data class

Protein

Predictors

HAMAP; MF_01559; [distribution of match scores in UniProtKB];[seed alignment for MF_01559]

Identifier

LLDD

Protein name

RecName: Full=L-lactate dehydrogenase [cytochrome]; EC=1.1.2.3;

Gene name

lldD

CATALYTIC ACTIVITY: (S)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c + 2 H(+).

COFACTOR: FMN (By similarity).

SUBUNIT: Homotetramer (By similarity).

SIMILARITY: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

SIMILARITY: Contains 1 FMN hydroxy acid dehydrogenase domain.

PROSITE	PS00557; FMN_HYDROXY_ACID_DH_1; 1; PS51349; FMN_HYDROXY_ACID_DH_2; 1; trigger=PRU00683;
Pfam	PF01070; FMN_dh; 1;

Flavoprotein, FMN, Oxidoreductase.

GO:0004460; Molecular function: L-lactate dehydrogenase (cytochrome) activity.

From: LLDD_ECOLI (P33232)
Key		From		To		Description		Condition		FTGroup
NP_BIND		306		330		FMN (By similarity)
ACT_SITE		275		275		Proton acceptor (By similarity)		H
BINDING		24		24		Substrate (Potential)		Y
BINDING		106		106		FMN (By similarity)		S
BINDING		127		127		FMN (By similarity)		Q
BINDING		129		129		Substrate (By similarity)		Y
BINDING		155		155		FMN (By similarity)		T
BINDING		164		164		Substrate (By similarity)		R
BINDING		251		251		FMN (By similarity)		K
BINDING		278		278		Substrate (Potential)		R

Size range:	378-396 amino acids
Related UniRules:	None
Template:	P33232 (LLDD_ECOLI)
Scope:	Bacteria; Proteobacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None