Accession	MF_01445
Dates	13-AUG-2007 (Created) 21-AUG-2008 (Last updated, Version 6)

Data class

Protein

Predictors

HAMAP; MF_01445; [distribution of match scores in UniProtKB];[seed alignment for MF_01445]

Identifier

GCP

Protein name

RecName: Full=Probable O-sialoglycoprotein endopeptidase; Short=Glycoprotease; EC=3.4.24.57;

Gene name

gcp

FUNCTION: Critical mediator involved in the modification of cell wall peptidoglycan synthesis and/or cell division. Essential for cell viability (By similarity).

CATALYTIC ACTIVITY: Hydrolysis of O-sialoglycoproteins; cleaves 31-Arg-|-Asp-32 bond in glycophorin A. Does not cleave unglycosylated proteins, desialylated glycoproteins or glycoproteins that are only N-glycosylated.

COFACTOR: Zinc (By similarity).

SIMILARITY: Belongs to the peptidase M22 family.

PROSITE	PS01016; GLYCOPROTEASE; 1;
Pfam	PF00814; Peptidase_M22; 1;
PRINTS	PR00789; OSIALOPTASE; 1;
TIGRFAMs	TIGR00329; gcp; 1;

Hydrolase, Metal-binding, Metalloprotease, Protease, Zinc.

GO:0004222; Molecular function: metalloendopeptidase activity.

From: GCP_PASHA (P36175)
Key		From		To		Description		Condition		FTGroup
METAL		111		111		Zinc (Potential)		H
METAL		115		115		Zinc (Potential)		H

Size range:	233-401 amino acids
Related UniRules:	None
Template:	P36175 (GCP_PASHA); Q2FWL2 (GCP_STAA8): [Recover all]
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None