Accession	MF_01400
Dates	8-APR-2002 (Created) 7-JUN-2008 (Last updated, Version 19)

Data class

Protein

Predictors

HAMAP; MF_01400; [distribution of match scores in UniProtKB];[seed alignment for MF_01400]

Identifier

MSRB

Protein name

RecName: Full=Peptide methionine sulfoxide reductase msrB; EC=1.8.4.12; AltName: Full=Peptide-methionine (R)-S-oxide reductase;

Gene name

msrB

CATALYTIC ACTIVITY: Peptide-L-methionine + thioredoxin disulfide + H(2)O = peptide-L-methionine (R)-S-oxide + thioredoxin.

COFACTOR: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein (By similarity).

SIMILARITY: Belongs to the msrB Met sulfoxide reductase family.

Pfam	PF01641; SelR; 1;
TIGRFAMs	TIGR00357; MsrB; 1;

Oxidoreductase.

Metal-binding, Zinc.

GO:0008113; Molecular function: peptide-methionine-(S)-S-oxide reductase activity.

GO:0008270; Molecular function: zinc ion binding.

From: MSRB_ECOLI (P0A746)
Key		From		To		Description		Condition		FTGroup
ACT_SITE		118		118		Nucleophile (By similarity)		C
METAL (Optional)		46		46		Zinc (By similarity)		C		1
METAL (Optional)		49		49		Zinc (By similarity)		C		1
METAL (Optional)		95		95		Zinc (By similarity)		C		1
METAL (Optional)		98		98		Zinc (By similarity)		C		1

Size range:	124-159 amino acids
Related UniRules:	None
Template:	P14930 (MSRAB_NEIGO); Q9JWM8 (MSRAB_NEIMA); P0A746 (MSRB_ECOLI); Q3JRF0 (MSRB_BURP1); P0A088 (MSRB_STAA8): [Recover all]
Scope:	Bacteria Archaea
Fusion:	Nter: MF_01401 (msrA); Cter: MF_01401 (msrA)
Duplicate:	in RHIME
Plasmid encoded:	in RHIME