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HAMAP annotation rule: MF_01270

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General rule information

Accession MF_01270
Dates 31-AUG-2006 (Created)
26-SEP-2008 (Last updated, Version 8)
Data class Protein
Predictors HAMAP; MF_01270; [distribution of match scores in UniProtKB];[seed alignment for MF_01270]


Propagated annotation

Identifier, protein and gene names
Identifier ANMK
Protein name
RecName: Full=Anhydro-N-acetylmuramic acid kinase;
EC=2.7.1.n1;
AltName: Full=AnhMurNAc kinase;
Gene name anmK
Comments
FUNCTION: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity).
CATALYTIC ACTIVITY: ATP + 1,6-anhydro-N-acetylmuramic acid + H(2)O = ADP + N-acetylmuramic acid 6-phosphate.
PATHWAY: Amino-sugar metabolism; anhydro-N-acetylmuramic acid degradation.
PATHWAY: Cell wall biogenesis; peptidoglycan recycling.
SIMILARITY: Belongs to the anhydro-N-acetylmuramic acid kinase family.
Cross-references
Pfam PF03702; UPF0075; 1;
Keywords
ATP-binding, Carbohydrate metabolism, Kinase, Nucleotide-binding, Transferase.
Gene Ontology
GO:0005524; Molecular function: ATP binding.
GO:0016773; Molecular function: phosphotransferase activity, alcohol group as acceptor.
GO:0006040; Biological process: amino sugar metabolic process.
GO:0009254; Biological process: peptidoglycan turnover.
Features
From: ANMK_ECOLI (P77570)
Key     From     To       Description   Condition   FTGroup
NP_BIND     12     19       ATP (Potential)      


Additional information

Size range: 355-436 amino acids
Related UniRules: None
Template: P77570 (ANMK_ECOLI)
Scope: Bacteria
Fusion: Nter: None; Cter: None
Duplicate: in JANSC
Plasmid encoded: in DEIGD

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UniProtKB rule member sequences



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