Accession	MF_01174
Dates	3-NOV-2006 (Created) 7-JUN-2008 (Last updated, Version 8)

Data class

Protein

Predictors

HAMAP; MF_01174; [distribution of match scores in UniProtKB];[seed alignment for MF_01174]

Identifier

ASTD

Protein name

RecName: Full=N-succinylglutamate 5-semialdehyde dehydrogenase; EC=1.2.1.71; AltName: Full=Succinylglutamic semialdehyde dehydrogenase; Short=SGSD;

Gene name

astD

FUNCTION: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate (By similarity).

CATALYTIC ACTIVITY: N-succinyl-L-glutamate 5-semialdehyde + NAD(+) + H(2)O = N-succinyl-L-glutamate + NADH.

PATHWAY: Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 4/5.

SIMILARITY: Belongs to the aldehyde dehydrogenase family. AstD subfamily.

PROSITE	PS00070; ALDEHYDE_DEHYDR_CYS; 1; PS00687; ALDEHYDE_DEHYDR_GLU; 1;
Pfam	PF00171; Aldedh; 1;

Arginine metabolism, NAD, Oxidoreductase.

GO:0016491; Molecular function: oxidoreductase activity.
GO:0019544; Biological process: arginine catabolic process to glutamate.

From: ASTD_ECOLI (P76217)
Key		From		To		Description		Condition		FTGroup
NP_BIND		220		225		NAD (By similarity)
ACT_SITE		243		243		By similarity		E
ACT_SITE		277		277		By similarity		C

Size range:	471-505 amino acids
Related UniRules:	None
Template:	P76217 (ASTD_ECOLI)
Scope:	Bacteria; Proteobacteria
Fusion:	Nter: None; Cter: None
Duplicate:	in CAUCR, PSEHT, SHEDO
Plasmid encoded:	None