| Accession |
MF_01006 |
| Dates |
1-MAR-2002 (Created)
30-JUN-2008 (Last updated, Version 31) |
case <OC:Bacteria>
| Protein name |
| RecName: |
Full=Undecaprenyl-diphosphatase;
EC=3.6.1.27; |
| AltName: |
Full=Undecaprenyl pyrophosphate phosphatase; |
| AltName: |
Full=Bacitracin resistance protein; |
|
end case
case <OC:Archaea>
| Protein name |
| RecName: |
Full=Undecaprenyl-diphosphatase;
EC=3.6.1.27; |
| AltName: |
Full=Undecaprenyl pyrophosphate phosphatase; |
|
end case
case <OC:Bacteria>
FUNCTION: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity).
end case
case <OC:Archaea>
FUNCTION: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) (By similarity).
end case
CATALYTIC ACTIVITY: Undecaprenyl diphosphate + H(2)O = undecaprenyl phosphate + phosphate.
case <Property:Membrane=1>
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (By similarity).
else case <Property:Membrane=2>
SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein (By similarity).
end case
case <OC:Bacteria>
MISCELLANEOUS: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
end case
SIMILARITY: Belongs to the uppP family.
| Pfam |
PF02673; BacA; 1;
|
| TIGRFAMs |
TIGR00753; undec_kin_bacA; 1;
|
| General |
Transmembrane; -; 5-9; trigger=Yes;
|
case <OC:Bacteria>
end case
case <Property:Membrane=2>
end case
case <OC:Bacteria>
end case
GO:0050380; Molecular function: undecaprenyl-diphosphatase activity.
case <OC:Bacteria>
GO:0046677; Biological process: response to antibiotic.
end case
| Size range: |
237-343 amino acids |
| Related UniRules: |
None |
| Template: |
P60932 (UPPP_ECOLI); P60934 (UPPP_STRPN): [Recover all] |
| Scope: |
Bacteria
Archaea |
| Fusion: |
Nter: None; Cter: None |
| Duplicate: |
in ACIAD, AGRT5, BACAH, BACAN, BACC1, BACCR, BACCZ, BACHD, BACHK, BACLD, BACSK, BURCA, BURCH, BURCM, BURP0, BURP1, BURPS, BURS3, BURTA, BURXL, CHRVO, CLOAB, CLOD6, CORJK, ENTFA, FRAAA, FRASC, MAGMM, OENOB, PSEHT, PSEPF, PSEU5, RHILO, RHORT, SHEON, STRAW, STRCO |
| Plasmid encoded: |
in CORST, ENTFA |
| Comments: |
UPPP2 from RHILO is shorter but can not easily be extended. |
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