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HAMAP annotation rule: MF_00821

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General rule information

Accession MF_00821
Dates 7-DEC-2005 (Created)
7-JUN-2008 (Last updated, Version 8)
Data class Protein
Predictors HAMAP; MF_00821; [distribution of match scores in UniProtKB];[seed alignment for MF_00821]


Propagated annotation

Identifier, protein and gene names
Identifier SECB
Protein name
RecName: Full=Protein-export protein secB;
Gene name secB
Comments
FUNCTION: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor secA (By similarity).
SUBUNIT: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 secA dimer (By similarity).
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the secB family.
Cross-references
Pfam PF02556; SecB; 1;
PRINTS PR01594; SECBCHAPRONE; 1;
TIGRFAMs TIGR00809; secB; 1;
Keywords
Cytoplasm, Chaperone, Protein transport, Translocation, Transport.
Gene Ontology
GO:0006457; Biological process: protein folding.
GO:0015031; Biological process: protein transport.
GO:0005737; Cellular component: cytoplasm.


Additional information

Size range: 140-188 amino acids
Related UniRules: None
Template: P0AG86 (SECB_ECOLI); P44853 (SECB_HAEIN): [Recover all]
Scope: Bacteria; Alphaproteobacteria
Bacteria; Betaproteobacteria
Bacteria; Gammaproteobacteria
Bacteria; Magnetococcus
Fusion: Nter: None; Cter: None
Duplicate: in FRAT1, FRATF, FRATH, FRATN, FRATO, FRATT, FRATW, GLUOX, POLNA
Plasmid encoded: None
Comments: Missing in some highly reduced Gammaproteobacteria, there is also a copy in the Deltaproteobacteria DESPS.

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UniProtKB rule member sequences



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