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HAMAP annotation rule: MF_00804

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General rule information

Accession MF_00804
Dates 20-JAN-2005 (Created)
7-JUN-2008 (Last updated, Version 13)
Data class Protein
Predictors HAMAP; MF_00804; [distribution of match scores in UniProtKB];[seed alignment for MF_00804]


Propagated annotation

Identifier, protein and gene names
Identifier BETB
Protein name
RecName: Full=Betaine aldehyde dehydrogenase;
Short=BADH;
EC=1.2.1.8;
Gene name betB
Comments
CATALYTIC ACTIVITY: Betaine aldehyde + NAD(+) + H(2)O = betaine + NADH.
PATHWAY: Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1.
SIMILARITY: Belongs to the aldehyde dehydrogenase family.
Cross-references
Pfam PF00171; Aldedh; 1;
TIGRFAMs TIGR01804; BADH; 1;
PROSITE PS00070; ALDEHYDE_DEHYDR_CYS; 1;
PS00687; ALDEHYDE_DEHYDR_GLU; 1;
Keywords
NAD, Oxidoreductase.
Gene Ontology
GO:0008802; Molecular function: betaine-aldehyde dehydrogenase activity.
GO:0019285; Biological process: glycine betaine biosynthetic process from choline.
Features
From: BETB_ECOLI (P17445)
Key     From     To       Description   Condition   FTGroup
NP_BIND     229     234       NAD (By similarity)   G-x(3)-[ST]-G  
ACT_SITE     252     252       By similarity   E  
ACT_SITE     286     286       By similarity   C  


Additional information

Size range: 481-493 amino acids
Related UniRules: None
Template: P17445 (BETB_ECOLI)
Scope: Bacteria; Proteobacteria
Fusion: Nter: None; Cter: None
Duplicate: in RHIME
Plasmid encoded: in RHIME

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UniProtKB rule member sequences



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