Accession	MF_00776
Dates	25-APR-2004 (Created) 5-AUG-2008 (Last updated, Version 11)

Data class

Protein

Predictors

HAMAP; MF_00776; [distribution of match scores in UniProtKB];[seed alignment for MF_00776]

Identifier

GYAR

Protein name

RecName: Full=Glyoxylate reductase; EC=1.1.1.26;

Gene name

gyaR

CATALYTIC ACTIVITY: Glycolate + NAD(+) = glyoxylate + NADH.

SUBUNIT: Homodimer (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GyaR subfamily.

Pfam	PF00389; 2-Hacid_dh; 1; PF02826; 2-Hacid_dh_C; 1;
PROSITE	PS00065; D_2_HYDROXYACID_DH_1; 1; PS00670; D_2_HYDROXYACID_DH_2; 1; PS00671; D_2_HYDROXYACID_DH_3; 1;

Cytoplasm, Oxidoreductase, NAD.

GO:0047964; Molecular function: glyoxylate reductase activity.
GO:0005737; Cellular component: cytoplasm.

From: GYAR_THELI (Q9C4M5)
Key		From		To		Description		Condition		FTGroup
NP_BIND		158		161		NADP (By similarity)		[FLM]-G-R-I
NP_BIND (Optional)		180		182		NADP (By similarity)		S-R-[ST]
NP_BIND		239		241		NADP (By similarity)		[ITV]-X-R
NP_BIND		288		290		NADP (By similarity)		H-X-[AG]
ACT_SITE		241		241		By similarity		R
ACT_SITE		270		270		By similarity		E
ACT_SITE		288		288		Proton donor (By similarity)		H

Size range:	331-339 amino acids
Related UniRules:	None
Template:	Q9C4M5 (GYAR_THELI); O58320 (GYAR_PYRHO): [Recover all]
Scope:	Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None