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HAMAP annotation rule: MF_00750

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Accession MF_00750
Dates 23-JAN-2004 (Created)
5-FEB-2010 (Last updated, Version 15)
Data class Protein
Names Choline_dehydrogen



Identifier BETA
Protein name
RecName: Full=Choline dehydrogenase;
Short=CHD;
Short=CDH;
EC=1.1.99.1;
Gene name betA
FUNCTION: Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity).
CATALYTIC ACTIVITY: Choline + acceptor = betaine aldehyde + reduced acceptor.
COFACTOR: FAD (By similarity).
PATHWAY: Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1.
SIMILARITY: Belongs to the GMC oxidoreductase family.
Pfam PF05199; GMC_oxred_C; 1;
PF00732; GMC_oxred_N; 1;
TIGRFAMs TIGR01810; betA; 1;
PROSITE PS00623; GMC_OXRED_1; 1;
PS00624; GMC_OXRED_2; 1;
GO:0008812; Molecular function: choline dehydrogenase activity.
GO:0019285; Biological process: glycine betaine biosynthetic process from choline.
From: BETA_ECOLI (P17444)
Key     From     To       Description   Condition   FTGroup
NP_BIND     4     33       FAD (Probable)      
ACT_SITE     473     473       By similarity   H  



Size range: 549-572 amino acids
Related UniRules: None
Template: P17444 (BETA_ECOLI)
Scope: Bacteria; Firmicutes
Bacteria; Proteobacteria
Fusion: Nter: None; Cter: None
Duplicate: None
Plasmid encoded: None

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