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HAMAP annotation rule: MF_00664

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General rule information

Accession MF_00664
Dates 28-JUN-2003 (Created)
4-DEC-2008 (Last updated, Version 16)
Data class Protein
Predictors HAMAP; MF_00664; [distribution of match scores in UniProtKB];[seed alignment for MF_00664]


Propagated annotation

Identifier, protein and gene names
Identifier PSD
Protein name
RecName: Full=Phosphatidylserine decarboxylase proenzyme;
EC=4.1.1.65;
RecName: Full=Phosphatidylserine decarboxylase alpha chain;
RecName: Full=Phosphatidylserine decarboxylase beta chain;
Gene name psd
Comments
CATALYTIC ACTIVITY: Phosphatidyl-L-serine = phosphatidylethanolamine + CO(2).
COFACTOR: Pyruvoyl group (By similarity).
PATHWAY: Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2.
SIMILARITY: Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.
Cross-references
Pfam PF02666; PS_Dcarbxylase; 1;
TIGRFAMs TIGR00164; PS_decarb_rel; 1;
Keywords
Phospholipid biosynthesis, Lyase, Decarboxylase, Pyruvate, Zymogen.
Gene Ontology
GO:0004609; Molecular function: phosphatidylserine decarboxylase activity.
GO:0008654; Biological process: phospholipid biosynthetic process.
Features
From: PSD_AGRT5 (Q8UGH4)
Key     From     To       Description   Condition   FTGroup
CHAIN     Nter     189       Phosphatidylserine decarboxylase beta chain (By similarity)      
CHAIN     190     Cter       Phosphatidylserine decarboxylase alpha chain (By similarity)      
SITE     189     190       Cleavage (non-hydrolytic) (By similarity)   G-S  
MOD_RES     190     190       Pyruvic acid (Ser) (By similarity)   S  


Additional information

Size range: 195-265 amino acids
Related UniRules: MF_00662 (PSD); MF_00663 (PSD)
Template: P0A8K1 (PSD_ECOLI)
Scope: Bacteria
Archaea
Fusion: Nter: None; Cter: None
Duplicate: None
Plasmid encoded: in SILPO, SILST

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UniProtKB rule member sequences



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