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HAMAP annotation rule: MF_00654

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General rule information

Accession MF_00654
Dates 13-JUN-2003 (Created)
4-DEC-2008 (Last updated, Version 18)
Data class Protein
Predictors HAMAP; MF_00654; [distribution of match scores in UniProtKB];[seed alignment for MF_00654]


Propagated annotation

Identifier, protein and gene names
Identifier PQQC
Protein name
RecName: Full=Pyrroloquinoline-quinone synthase;
EC=1.3.3.11;
AltName: Full=Coenzyme PQQ synthesis protein C;
AltName: Full=Pyrroloquinoline quinone biosynthesis protein C;
Gene name pqqC
Comments
FUNCTION: Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ (By similarity).
CATALYTIC ACTIVITY: 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O(2) = 4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate + 2 H(2)O(2) + 2 H(2)O.
PATHWAY: Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.
SIMILARITY: Belongs to the pqqC family.
Cross-references
Pfam PF05312; PQQC; 1;
Keywords
Oxidoreductase, PQQ biosynthesis.
Gene Ontology
GO:0018189; Biological process: pyrroloquinoline quinone biosynthetic process.


Additional information

Size range: 239-268 amino acids
Related UniRules: None
Template: P27505 (PQQC_KLEPN)
Scope: Bacteria
Fusion: Nter: None; Cter: MF_00655 (pqqD)
Duplicate: None
Plasmid encoded: in RHIME

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UniProtKB rule member sequences



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