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HAMAP annotation rule: MF_00628

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General rule information

Accession MF_00628
Dates 24-MAR-2003 (Created)
7-JUN-2008 (Last updated, Version 13)
Data class Protein
Predictors HAMAP; MF_00628; [distribution of match scores in UniProtKB];[seed alignment for MF_00628]


Propagated annotation

Identifier, protein and gene names
Identifier PTH
Protein name
RecName: Full=Peptidyl-tRNA hydrolase;
Short=PTH;
EC=3.1.1.29;
Gene name pth
Comments
FUNCTION: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis (By similarity).
CATALYTIC ACTIVITY: N-substituted aminoacyl-tRNA + H(2)O = N-substituted amino acid + tRNA.
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the PTH2 family.
Cross-references
Pfam PF01981; UPF0099; 1;
TIGRFAMs TIGR00283; UPF0099; 1;
Keywords
Cytoplasm, Hydrolase.
Gene Ontology
GO:0004045; Molecular function: aminoacyl-tRNA hydrolase activity.
GO:0006412; Biological process: translation.
GO:0005737; Cellular component: cytoplasm.


Additional information

Size range: 112-124 amino acids
Related UniRules: None
Template: Q60363 (PTH_METJA); Q980V1 (PTH_SULSO): [Recover all]
Scope: Archaea
Fusion: Nter: None; Cter: None
Duplicate: None
Plasmid encoded: None

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UniProtKB rule member sequences



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