Accession	MF_00564
Dates	27-JUN-2002 (Created) 7-JUN-2008 (Last updated, Version 14)

Data class

Protein

Predictors

HAMAP; MF_00564; [distribution of match scores in UniProtKB];[seed alignment for MF_00564]

Identifier

RNPH

Protein name

RecName: Full=Ribonuclease PH; Short=RNase PH; EC=2.7.7.56; AltName: Full=tRNA nucleotidyltransferase;

Gene name

rph

FUNCTION: Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity).

CATALYTIC ACTIVITY: tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate.

SIMILARITY: Belongs to the RNase PH family.

Pfam	PF01138; RNase_PH; 1; PF03725; RNase_PH_C; 1;
PROSITE	PS01277; RIBONUCLEASE_PH; 1;

Transferase, Nucleotidyltransferase, tRNA processing.

GO:0000049; Molecular function: tRNA binding.
GO:0009022; Molecular function: tRNA nucleotidyltransferase activity.
GO:0008033; Biological process: tRNA processing.

Size range:	235-261 amino acids
Related UniRules:	MF_00591 (ECX1); MF_00622 (ECX2)
Template:	P28619 (RNPH_BACSU); P03842 (RNPH_ECOLI): [Recover all]
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None