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HAMAP annotation rule: MF_00555

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General rule information

Accession MF_00555
Dates 16-MAY-2002 (Created)
23-MAR-2009 (Last updated, Version 22)
Data class Protein
Predictors HAMAP; MF_00555; [distribution of match scores in UniProtKB];[seed alignment for MF_00555]


Propagated annotation

Identifier, protein and gene names
Identifier ASNA
Protein name
RecName: Full=Aspartate--ammonia ligase;
EC=6.3.1.1;
AltName: Full=Asparagine synthetase A;
Gene name asnA
Comments
CATALYTIC ACTIVITY: ATP + L-aspartate + NH(3) = AMP + diphosphate + L-asparagine.
PATHWAY: Amino-acid biosynthesis; L-asparagine biosynthesis; L-asparagine from L-aspartate (ammonia route): step 1/1.
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
Cross-references
Pfam PF03590; AsnA; 1;
TIGRFAMs TIGR00669; asnA; 1;
PROSITE PS50862; AA_TRNA_LIGASE_II; 1;
Keywords
Amino-acid biosynthesis, Asparagine biosynthesis, ATP-binding, Cytoplasm, Ligase, Nucleotide-binding.
Gene Ontology
GO:0004071; Molecular function: aspartate-ammonia ligase activity.
GO:0005524; Molecular function: ATP binding.
GO:0006529; Biological process: asparagine biosynthetic process.
GO:0005737; Cellular component: cytoplasm.


Additional information

Size range: 322-345 amino acids
Related UniRules: None
Template: P00963 (ASNA_ECOLI)
Scope: Bacteria
Fusion: Nter: None; Cter: None
Duplicate: None
Plasmid encoded: None

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UniProtKB rule member sequences



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