Accession	MF_00523
Dates	13-JAN-2002 (Created) 24-NOV-2008 (Last updated, Version 21)

Data class

Protein

Predictors

HAMAP; MF_00523; [distribution of match scores in UniProtKB];[seed alignment for MF_00523]

Identifier

LPXD

Protein name

RecName: Full=UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; EC=2.3.1.-;

Gene name

lpxD

CATALYTIC ACTIVITY: UDP-3-O-(3-hydroxytetradecanoyl)glucosamine + (R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] = UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + [acyl-carrier-protein].

PATHWAY: Glycolipid biosynthesis; lipid (IV)A biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-D-glucosamine: step 3/6.

SIMILARITY: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.

Pfam	PF00132; hexapep; 1;
PROSITE	PS00101; HEXAPEP_TRANSFERASES; 1-4;

Transferase, Acyltransferase, Lipid A biosynthesis, Lipid synthesis, Repeat.

GO:0016747; Molecular function: transferase activity, transferring acyl groups other than amino-acyl groups.
GO:0009245; Biological process: lipid A biosynthetic process.

Size range:	316-380 amino acids
Related UniRules:	MF_00387 (LPXA)
Template:	P21645 (LPXD_ECOLI)
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	in ACIBL, FRAT1, FRATH, FRATO, FRATT, GLOVI, LEGPA, LEGPH, LEGPL, NITWN, RHOPB, SULDN
Plasmid encoded:	None