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HAMAP annotation rule: MF_00519

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General rule information

Accession MF_00519
Dates 18-DEC-2001 (Created)
4-DEC-2008 (Last updated, Version 17)
Data class Protein
Predictors HAMAP; MF_00519; [distribution of match scores in UniProtKB];[seed alignment for MF_00519]


Propagated annotation

Identifier, protein and gene names
Identifier ARAA
Protein name
RecName: Full=L-arabinose isomerase;
EC=5.3.1.4;
Gene name araA
Comments
FUNCTION: Catalyzes the conversion of L-arabinose to L-ribulose (By similarity).
CATALYTIC ACTIVITY: L-arabinose = L-ribulose.

case <FTGroup:1>
COFACTOR: Binds 1 manganese ion per subunit (By similarity).
end case

PATHWAY: Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacteria route): step 1/3.

case <OC:Enterobacteriaceae>
SUBUNIT: Homohexamer (By similarity).
end case

SIMILARITY: Belongs to the arabinose isomerase family.
Cross-references
Pfam PF02610; Arabinose_Isome; 1;
Keywords
Arabinose catabolism, Carbohydrate metabolism, Isomerase.

case <FTGroup:1>
Manganese, Metal-binding.
end case

Gene Ontology
GO:0008733; Molecular function: L-arabinose isomerase activity.

case <FTGroup:1>
GO:0030145; Molecular function: manganese ion binding.
end case

GO:0019568; Biological process: arabinose catabolic process.
Features
From: ARAA_ECOLI (P08202)
Key     From     To       Description   Condition   FTGroup
METAL     306     306       Manganese (By similarity)   E   1
METAL     333     333       Manganese (By similarity)   E   1
METAL     350     350       Manganese (By similarity)   H   1
METAL     450     450       Manganese (By similarity)   H   1


Additional information

Size range: 474-511 amino acids
Related UniRules: None
Template: P08202 (ARAA_ECOLI); Q9S467 (ARAA_BACST): [Recover all]
Scope: Bacteria
Fusion: Nter: None; Cter: None
Duplicate: in BACLD, CLOAB
Plasmid encoded: None

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UniProtKB rule member sequences



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