Accession	MF_00455
Dates	24-SEP-2001 (Created) 4-MAR-2009 (Last updated, Version 27)

Data class

Protein

Predictors

HAMAP; MF_00455; [distribution of match scores in UniProtKB];[seed alignment for MF_00455]

Identifier

XYLA

Protein name

RecName: Full=Xylose isomerase; EC=5.3.1.5;

Gene name

xylA

CATALYTIC ACTIVITY: D-xylose = D-xylulose.

COFACTOR: Binds 2 magnesium ions per subunit (By similarity).

SUBUNIT: Homotetramer (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the xylose isomerase family.

Pfam	PF00259; Xylose_isom; 1;
PRINTS	PR00688; XYLOSISMRASE; 1;
PROSITE	PS51415; XYLOSE_ISOMERASE; 1;

Cytoplasm, Isomerase, Pentose shunt, Carbohydrate metabolism, Xylose metabolism, Magnesium, Metal-binding.

GO:0000287; Molecular function: magnesium ion binding.
GO:0009045; Molecular function: xylose isomerase activity.
GO:0042732; Biological process: D-xylose metabolic process.
GO:0006098; Biological process: pentose-phosphate shunt.
GO:0005737; Cellular component: cytoplasm.

From: XYLA_ACTMI (P12851)
Key		From		To		Description		Condition		FTGroup
ACT_SITE		54		54		By similarity		H
ACT_SITE		57		57		By similarity		[DE]
METAL		181		181		Magnesium 1 (By similarity)		E
METAL		217		217		Magnesium 1 (By similarity)		E
METAL		217		217		Magnesium 2 (By similarity)		E
METAL		220		220		Magnesium 2 (By similarity)		H
METAL		245		245		Magnesium 1 (By similarity)		D
METAL		255		255		Magnesium 2 (By similarity)		D
METAL		257		257		Magnesium 2 (By similarity)		D
METAL		292		292		Magnesium 1 (By similarity)		D

From: XYLA_ECOLI (P00944)
Key		From		To		Description		Condition		FTGroup
ACT_SITE		101		101		By similarity		H
ACT_SITE		104		104		By similarity		[DE]
METAL		232		232		Magnesium 1 (By similarity)		E
METAL		268		268		Magnesium 1 (By similarity)		E
METAL		268		268		Magnesium 2 (By similarity)		E
METAL		271		271		Magnesium 2 (By similarity)		H
METAL		296		296		Magnesium 1 (By similarity)		D
METAL		307		307		Magnesium 2 (By similarity)		D
METAL		309		309		Magnesium 2 (By similarity)		D
METAL		339		339		Magnesium 1 (By similarity)		D

Size range:	386-449 amino acids
Related UniRules:	None
Template:	P12851 (XYLA_ACTMI); P12070 (XYLA_ARTS7); P54272 (XYLA_BACSW); P00944 (XYLA_ECOLI); P15587 (XYLA_STROL): [Recover all]
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	in XANAC, XANC8, XANCP, XANOR
Plasmid encoded:	None