ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us HAMAP Swiss-Prot
Search for

HAMAP annotation rule: MF_00406

Send feedback new

General rule information

Accession MF_00406
Dates 1-JUN-2001 (Created)
7-JUN-2008 (Last updated, Version 22)
Data class Protein
Predictors HAMAP; MF_00406; [distribution of match scores in UniProtKB];[seed alignment for MF_00406]


Propagated annotation

Identifier, protein and gene names
Identifier FABZ
Protein name
RecName: Full=(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase;
Short=(3R)-hydroxymyristoyl ACP dehydrase;
EC=4.2.1.-;
Gene name fabZ
Comments
FUNCTION: Involved in saturated fatty acids biosynthesis (By similarity).

case <OC:Escherichia> or <OC:Shigella>
SUBUNIT: Oligomer (By similarity).
end case

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

case <OC:Escherichia> or <OC:Shigella>
PTM: The N-terminus is blocked (By similarity).
end case

SIMILARITY: Belongs to the thioester dehydratase family. FabZ subfamily.
Cross-references
Pfam PF01377; Thioester_dehyd; 1;
Keywords
Cytoplasm, Lyase, Lipid synthesis, Lipid A biosynthesis.
Gene Ontology
GO:0016836; Molecular function: hydro-lyase activity.
GO:0009245; Biological process: lipid A biosynthetic process.
GO:0005737; Cellular component: cytoplasm.
Features
From: FABZ_ECOLI (P0A6Q6)
Key     From     To       Description   Condition   FTGroup
ACT_SITE     54     54       By similarity   H  


Additional information

Size range: 132-181 amino acids
Related UniRules: MF_00405 (FABA)
Template: P0A6Q6 (FABZ_ECOLI)
Scope: Bacteria
Fusion: Nter: MF_00388 (lpxC); Cter: None
Duplicate: in LACLA
Plasmid encoded: None
Comments: Possible wrong start in SYNY3

View rule in raw text format (no links)




UniProtKB rule member sequences



ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us HAMAP Swiss-Prot