Accession	MF_00403
Dates	1-JUN-2001 (Created) 25-SEP-2008 (Last updated, Version 33)

Data class

Protein

Predictors

HAMAP; MF_00403_B; [distribution of match scores in UniProtKB];[seed alignment for MF_00403_B]

Predictors

HAMAP; MF_00403_A; [distribution of match scores in UniProtKB];[seed alignment for MF_00403_A]

Identifier

RS12

Protein name

RecName: Full=30S ribosomal protein S12;

Gene name

rpsL

Identifier

RS12

Protein name

RecName: Full=30S ribosomal protein S12;

Gene name

rpsL, rps12

Identifier

RS12

Protein name

RecName: Full=30S ribosomal protein S12P;

Gene name

rps12p

Identifier

RR12

Protein name

RecName: Full=30S ribosomal protein S12, chloroplastic;

Gene name

rps12

FUNCTION: With S4 and S5 plays an important role in translational accuracy (By similarity).

FUNCTION: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity).

SUBUNIT: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex (By similarity).

FUNCTION: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits (By similarity).

SUBUNIT: Part of the 30S ribosomal subunit (By similarity).

FUNCTION: With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits (By similarity).

SUBUNIT: Part of the 30S ribosomal subunit (By similarity).

SUBCELLULAR LOCATION: Plastid, chloroplast.

SIMILARITY: Belongs to the ribosomal protein S12P family.

Pfam	PF00164; Ribosomal_S12; 1;
PRINTS	PR01034; RIBOSOMALS12; 1;
TIGRFAMs	TIGR00981; rpsL_bact; 1; TIGR00982; S23_S12_E_A; 1;
PROSITE	PS00055; RIBOSOMAL_S12; 1;

Acetylation.

Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding.

tRNA-binding.

GO:0019843; Molecular function: rRNA binding.

GO:0000049; Molecular function: tRNA binding.

GO:0006412; Biological process: translation.

GO:0009507; Cellular component: chloroplast.

From: RS12_ECOLI (P0A7S3)
Key		From		To		Description		Condition		FTGroup
MOD_RES		89		89		3-methylthioaspartic acid (By similarity)		D

Key		From		To		Description		Condition		FTGroup
MOD_RES		108		108		N6-acetyllysine (By similarity)		K

Size range:

117-144 amino acids

Size range:

141-151 amino acids

Related UniRules:	None
Template:	P21472 (RS12_BACSU); P0A7S3 (RS12_ECOLI); Q6N4T2 (RS12_RHOPA); Q5SHN3 (RS12_THET8); P14149 (RR12_CHLRE): [Recover all]
Scope:	Bacteria Archaea Plastid
Fusion:	Nter: None; Cter: None
Duplicate:	in AQUAE, BARBK, RHOS1
Plasmid encoded:	None