Accession	MF_00377
Dates	1-JUN-2001 (Created) 7-JUN-2008 (Last updated, Version 24)

Data class

Protein

Predictors

HAMAP; MF_00377; [distribution of match scores in UniProtKB];[seed alignment for MF_00377]

Identifier

DNAA

Protein name

RecName: Full=Chromosomal replication initiator protein dnaA;

Gene name

dnaA

FUNCTION: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the dnaA family.

Pfam	PF00308; bac_dnaA; 1;
PRINTS	PR00051; DNAA; 1;
TIGRFAMs	TIGR00362; DnaA; 1;
PROSITE	PS01008; DNAA; 1;

Cytoplasm, DNA replication, DNA-binding, ATP-binding, Nucleotide-binding.

GO:0005524; Molecular function: ATP binding.
GO:0003688; Molecular function: DNA replication origin binding.
GO:0006270; Biological process: DNA replication initiation.
GO:0006275; Biological process: regulation of DNA replication.
GO:0005737; Cellular component: cytoplasm.

From: DNAA_ECOLI (P03004)
Key		From		To		Description		Condition		FTGroup
NP_BIND		172		179		ATP (Potential)		[GSA]-x(2)-[GS]-x-G-K-[ST]

Size range:	399-656 amino acids
Related UniRules:	None
Template:	P03004 (DNAA_ECOLI); P05648 (DNAA_BACSU): [Recover all]
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	in CHLMU, CHLPN, CHLTR
Plasmid encoded:	None