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HAMAP annotation rule: MF_00361


General rule information

Accession MF_00361
Dates 1-JUN-2001 (Created)
7-JUN-2008 (Last updated, Version 17)
Data class Protein
Predictors HAMAP; MF_00361; [distribution of match scores in UniProtKB];[seed alignment for MF_00361]


Propagated annotation

Identifier, protein and gene names
Identifier PPNK
Protein name
RecName: Full=Probable inorganic polyphosphate/ATP-NAD kinase;
Short=Poly(P)/ATP NAD kinase;
EC=2.7.1.23;
Gene name ppnK
Comments
FUNCTION: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity).
CATALYTIC ACTIVITY: ATP + NAD(+) = ADP + NADP(+).
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
COFACTOR: Divalent metal ions (By similarity).
SIMILARITY: Belongs to the NAD kinase family.
Cross-references
Pfam PF01513; NAD_kinase; 1;
Keywords
Cytoplasm, Transferase, Kinase, NAD, NADP.
Gene Ontology
GO:0046872; Molecular function: metal ion binding.
GO:0003951; Molecular function: NAD+ kinase activity.
GO:0005737; Cellular component: cytoplasm.


Additional information

Size range: 248-363 amino acids
Related UniRules: None
Template: P0A5S6 (PPNK_MYCTU)
Scope: Bacteria
Archaea
Fusion: Nter: <Unknown>; Cter: None
Duplicate: in ANASP, BACHD, BACSU, LISIN, LISMO, SYNY3
Plasmid encoded: None
Comments: Unknown N-terminal domain in METJA and METMP

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UniProtKB rule member sequences



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