HAMAP family: MF

General rule information

Accession	MF_00333
Dates	1-JUN-2001 (Created) 5-MAY-2009 (Last updated, Version 28)

Data class

Protein

Predictors

HAMAP; MF_00333; [distribution of match scores in UniProtKB];[seed alignment for MF_00333]

Propagated annotation

Identifier, protein and gene names

Identifier

HEM6

Protein name

RecName:

Full=Coproporphyrinogen-III oxidase, aerobic;
Short=Coproporphyrinogenase;
Short=Coprogen oxidase;
EC=1.3.3.3;

Gene name

hemF

Comments

CATALYTIC ACTIVITY: Coproporphyrinogen-III + O(2) + 2 H(+) = protoporphyrinogen-IX + 2 CO(2) + 2 H(2)O.

case <OC:Escherichia> or <OC:Shigella>

COFACTOR: Manganese (By similarity).

end case

PATHWAY: Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1.

case <OC:Escherichia> or <OC:Shigella>

SUBUNIT: Homodimer (By similarity).

end case

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the aerobic coproporphyrinogen-III oxidase family.

Cross-references

Pfam	PF01218; Coprogen_oxidas; 1;
PRINTS	PR00073; COPRGNOXDASE; 1;
PROSITE	PS01021; COPROGEN_OXIDASE; 1;

Keywords

Cytoplasm, Porphyrin biosynthesis, Oxidoreductase.

case <OC:Escherichia> or <OC:Shigella>

Manganese.

end case

Gene Ontology

GO:0004109; Molecular function: coproporphyrinogen oxidase activity.
GO:0006779; Biological process: porphyrin biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Additional information

Size range:	279-363 amino acids
Related UniRules:	None
Template:	P36553 (HEM6_ECOLI)
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	in ANASP
Plasmid encoded:	None

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