Accession	MF_00328
Dates	1-JUN-2001 (Created) 7-JUN-2008 (Last updated, Version 18)

Data class

Protein

Predictors

HAMAP; MF_00328; [distribution of match scores in UniProtKB];[seed alignment for MF_00328]

Identifier

KGUA

Protein name

RecName: Full=Guanylate kinase; EC=2.7.4.8; AltName: Full=GMP kinase;

Gene name

gmk

FUNCTION: Essential for recycling GMP and indirectly, cGMP (By similarity).

CATALYTIC ACTIVITY: ATP + GMP = ADP + GDP.

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the guanylate kinase family.

SIMILARITY: Contains 1 guanylate kinase-like domain.

Pfam	PF00625; Guanylate_kin; 1;
PROSITE	PS00856; GUANYLATE_KINASE_1; 1; PS50052; GUANYLATE_KINASE_2; 1; trigger=PRU00100;

Cytoplasm, Transferase, Kinase, ATP-binding, Nucleotide-binding.

GO:0005524; Molecular function: ATP binding.
GO:0004385; Molecular function: guanylate kinase activity.
GO:0006163; Biological process: purine nucleotide metabolic process.
GO:0005737; Cellular component: cytoplasm.

From: KGUA_ECOLI (P60546)
Key		From		To		Description		Condition		FTGroup
NP_BIND		11		18		ATP (By similarity)		[GSA]-x-[SAT]-[GA]-x-G-K-x

Size range:	176-254 amino acids
Related UniRules:	None
Template:	P60546 (KGUA_ECOLI); P15454 (KGUA_YEAST): [Recover all]
Scope:	Bacteria
Fusion:	Nter: None; Cter: <Unknown>
Duplicate:	None
Plasmid encoded:	None
Comments:	Possible wrong start in MYCGE and MYCPN