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HAMAP annotation rule: MF_00300

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General rule information

Accession MF_00300
Dates 1-JUN-2001 (Created)
23-SEP-2008 (Last updated, Version 25)
Data class Protein

case <OC:Bacteria>
Predictors HAMAP; MF_00300_B; [distribution of match scores in UniProtKB];[seed alignment for MF_00300_B]
end case


case <OC:Archaea>
Predictors HAMAP; MF_00300_A; [distribution of match scores in UniProtKB];[seed alignment for MF_00300_A]
end case



Propagated annotation

Identifier, protein and gene names
Identifier AROC
Protein name
RecName: Full=Chorismate synthase;
EC=4.2.3.5;
AltName: Full=5-enolpyruvylshikimate-3-phosphate phospholyase;
Gene name aroC
Comments
CATALYTIC ACTIVITY: 5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate.
COFACTOR: Reduced flavin (By similarity).
PATHWAY: Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and PEP: step 7/7.

case <OC:Bacteria>
SUBUNIT: Homotetramer (By similarity).
end case

SIMILARITY: Belongs to the chorismate synthase family.
Cross-references
Pfam PF01264; Chorismate_synt; 1;
TIGRFAMs TIGR00033; aroC; 1;
PROSITE PS00787; CHORISMATE_SYNTHASE_1; 1;
PS00788; CHORISMATE_SYNTHASE_2; 1;
PS00789; CHORISMATE_SYNTHASE_3; 1;
Keywords
Lyase, Amino-acid biosynthesis, Aromatic amino acid biosynthesis.
Gene Ontology
GO:0004107; Molecular function: chorismate synthase activity.
GO:0009073; Biological process: aromatic amino acid family biosynthetic process.


Additional information


case <OC:Bacteria>
Size range: 350-422 amino acids
end case


case <OC:Archaea>
Size range: 355-399 amino acids
end case

Related UniRules: None
Template: P12008 (AROC_ECOLI)
Scope: Bacteria
Archaea
Fusion: Nter: None; Cter: None
Duplicate: None
Plasmid encoded: None
Comments: Possible wrong start in DEIRA

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UniProtKB rule member sequences



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