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HAMAP annotation rule: MF_00254

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General rule information

Accession MF_00254
Dates 1-JUN-2001 (Created)
7-JUN-2008 (Last updated, Version 18)
Data class Protein
Predictors HAMAP; MF_00254; [distribution of match scores in UniProtKB];[seed alignment for MF_00254]


Propagated annotation

Identifier, protein and gene names
Identifier SYGA
Protein name
RecName: Full=Glycyl-tRNA synthetase alpha subunit;
EC=6.1.1.14;
AltName: Full=Glycine--tRNA ligase alpha subunit;
Short=GlyRS;
Gene name glyQ
Comments
CATALYTIC ACTIVITY: ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).
SUBUNIT: Tetramer of two alpha and two beta subunits (By similarity).
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
Cross-references
Pfam PF02091; tRNA_synt_2e; 1;
PRINTS PR01044; TRNASYNTHGA; 1;
TIGRFAMs TIGR00388; glyQ; 1;
PROSITE PS50861; AA_TRNA_LIGASE_II_GLYAB; 1;
Keywords
Cytoplasm, Aminoacyl-tRNA synthetase, Protein biosynthesis, Ligase, ATP-binding, Nucleotide-binding.
Gene Ontology
GO:0005524; Molecular function: ATP binding.
GO:0004820; Molecular function: glycine-tRNA ligase activity.
GO:0006426; Biological process: glycyl-tRNA aminoacylation.
GO:0005737; Cellular component: cytoplasm.


Additional information

Size range: 285-319 amino acids
Related UniRules: None
Template: O23627 (SYGM1_ARATH)
Scope: Bacteria
Fusion: Nter: None; Cter: MF_00255 (glyS)
Duplicate: None
Plasmid encoded: None
Comments: glyQ and glyS are fused in Chlamydia. Possible wrong start in XYLFA.

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UniProtKB rule member sequences



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