Accession	MF_00149
Dates	1-JUN-2001 (Created) 7-JUN-2008 (Last updated, Version 12)

Data class

Protein

Predictors

HAMAP; MF_00149; [distribution of match scores in UniProtKB];[seed alignment for MF_00149]

Identifier

MUTL

Protein name

RecName: Full=DNA mismatch repair protein mutL;

Gene name

mutL

FUNCTION: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a "molecular matchmaker", a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity).

SIMILARITY: Belongs to the DNA mismatch repair mutL/hexB family.

Pfam	PF01119; DNA_mis_repair; 1; PF02518; HATPase_c; 1;
TIGRFAMs	TIGR00585; mutl; 1;
PROSITE	PS00058; DNA_MISMATCH_REPAIR_1; 1;

DNA damage, DNA repair.

GO:0006298; Biological process: mismatch repair.

Size range:	425-674 amino acids
Related UniRules:	None
Template:	P23367 (MUTL_ECOLI)
Scope:	Bacteria Archaea
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None