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HAMAP annotation rule: MF_00141

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General rule information

Accession MF_00141
Dates 1-JUN-2001 (Created)
7-JUN-2008 (Last updated, Version 18)
Data class Protein
Predictors HAMAP; MF_00141; [distribution of match scores in UniProtKB];[seed alignment for MF_00141]


Propagated annotation

Identifier, protein and gene names
Identifier EFP
Protein name
RecName: Full=Elongation factor P;
Short=EF-P;
Gene name efp
Comments
FUNCTION: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity).
PATHWAY: Protein biosynthesis; polypeptide chain elongation.
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the elongation factor P family.
Cross-references
Pfam PF01132; EFP; 1;
TIGRFAMs TIGR00038; efp; 1;
PROSITE PS01275; EFP; 1;
Keywords
Cytoplasm, Protein biosynthesis, Elongation factor.
Gene Ontology
GO:0003746; Molecular function: translation elongation factor activity.
GO:0006414; Biological process: translational elongation.
GO:0005737; Cellular component: cytoplasm.


Additional information

Size range: 184-195 amino acids
Related UniRules: MF_00646 (EFPL)
Template: P0A6N4 (EFP_ECOLI); Q76G20 (EFP_THET8): [Recover all]
Scope: Bacteria
Fusion: Nter: None; Cter: None
Duplicate: in CHLMU, CHLPN, CHLTR, LACJO, PARUW, PORGI, RHILO
Plasmid encoded: None

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UniProtKB rule member sequences



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