Accession	MF_00129
Dates	1-JUN-2001 (Created) 27-JUN-2008 (Last updated, Version 23)

Data class

Protein

Predictors

HAMAP; MF_00129; [distribution of match scores in UniProtKB];[seed alignment for MF_00129]

Identifier

MNMG

Protein name

RecName: Full=tRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmG; AltName: Full=Glucose-inhibited division protein A;

Gene name

mnmG, gidA

FUNCTION: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity).

COFACTOR: FAD (By similarity).

SUBUNIT: Homodimer (By similarity). Heterotetramer of two mnmE and two mnmG subunits (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the mnmG family.

Pfam	PF01134; GIDA; 1;
TIGRFAMs	TIGR00136; gidA; 1;
PROSITE	PS01280; GIDA_1; 1; PS01281; GIDA_2; 1;

Cytoplasm, FAD, Flavoprotein, NAD, tRNA processing.

GO:0050660; Molecular function: FAD binding.
GO:0008033; Biological process: tRNA processing.
GO:0005737; Cellular component: cytoplasm.

From: MNMG_ECOLI (P0A6U3)
Key		From		To		Description		Condition		FTGroup
NP_BIND		13		18		FAD (By similarity)		G-[GATL]-G-H-[AS]-G
NP_BIND		273		287		NAD (Potential)		[GSA]-x-[RL]-[YH]-C-P-S-[IVFL]-[ED]-x-K-[VIFAL]-x-x-[FY]
BINDING (Optional)		125		125		FAD; via amide nitrogen and carbonyl oxygen (By similarity)		[VI]		1
BINDING (Optional)		180		180		FAD (By similarity)		[ST]		1
BINDING (Optional)		370		370		FAD (By similarity)		[QN]		1

Size range:	500-685 amino acids
Related UniRules:	None
Template:	P0A6U3 (MNMG_ECOLI); O66962 (MNMG_AQUAE); Q8KA85 (MNMG_CHLTE): [Recover all]
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	in FUSNN, MYCMS, THETN
Plasmid encoded:	None