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HAMAP annotation rule: MF_00126


General rule information

Accession MF_00126
Dates 1-JUN-2001 (Created)
7-JUN-2008 (Last updated, Version 20)
Data class Protein
Predictors HAMAP; MF_00126; [distribution of match scores in UniProtKB];[seed alignment for MF_00126]


Propagated annotation

Identifier, protein and gene names
Identifier SYQ
Protein name
RecName: Full=Glutaminyl-tRNA synthetase;
EC=6.1.1.18;
AltName: Full=Glutamine--tRNA ligase;
Short=GlnRS;
Gene name glnS
Comments
CATALYTIC ACTIVITY: ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).
SUBUNIT: Monomer (By similarity).
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
Cross-references
Pfam PF00749; tRNA-synt_1c; 1;
PRINTS PR00987; TRNASYNTHGLU; 1;
TIGRFAMs TIGR00440; glnS; 1;
PROSITE PS00178; AA_TRNA_LIGASE_I; 1;
Keywords
Cytoplasm, Aminoacyl-tRNA synthetase, Protein biosynthesis, Ligase, ATP-binding, Nucleotide-binding.
Gene Ontology
GO:0005524; Molecular function: ATP binding.
GO:0004819; Molecular function: glutamine-tRNA ligase activity.
GO:0006424; Biological process: glutamyl-tRNA aminoacylation.
GO:0005737; Cellular component: cytoplasm.
Features
From: SYQ_ECOLI (P00962)
Key     From     To       Description   Condition   FTGroup
MOTIF     34     44       "HIGH" region   P-[ED]-P-[NS]-G-[YF]-x-H-[LI]-G-H  
MOTIF     268     272       "KMSKS" region   [LVI]-[LMT]-S-K-R  
BINDING     271     271       ATP (By similarity)   K  


Additional information

Size range: 552-636 amino acids
Related UniRules: None
Template: P00962 (SYQ_ECOLI)
Scope: Bacteria
Fusion: Nter: None; Cter: MF_00121 (gatB)
Duplicate: None
Plasmid encoded: None
Comments: Partial gatB like C-terminal domain in DEIRA. Possible wrong start site in DEIRA.

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UniProtKB rule member sequences



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