Accession	MF_00101
Dates	1-JUN-2001 (Created) 7-JUN-2008 (Last updated, Version 26)

Data class

Protein

Predictors

HAMAP; MF_00101; [distribution of match scores in UniProtKB];[seed alignment for MF_00101]

Identifier

ACPS

Protein name

RecName: Full=Holo-[acyl-carrier-protein] synthase; Short=Holo-ACP synthase; EC=2.7.8.7; AltName: Full=4'-phosphopantetheinyl transferase acpS;

Gene name

acpS

FUNCTION: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity).

CATALYTIC ACTIVITY: CoA-(4'-phosphopantetheine) + apo-[acyl-carrier-protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier-protein].

COFACTOR: Magnesium (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the P-Pant transferase superfamily. AcpS family.

Pfam	PF01648; ACPS; 1;
TIGRFAMs	TIGR00516; acpS; 1; TIGR00556; pantethn_trn; 1;

Cytoplasm, Transferase, Lipid synthesis, Fatty acid biosynthesis.

Magnesium, Metal-binding.

GO:0008897; Molecular function: holo-[acyl-carrier-protein] synthase activity.

GO:0000287; Molecular function: magnesium ion binding.

GO:0006633; Biological process: fatty acid biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

From: ACPS_ECOLI (P24224)
Key		From		To		Description		Condition		FTGroup
METAL		9		9		Magnesium (By similarity)		[DE]
METAL		58		58		Magnesium (By similarity)		[EQ]

Size range:	108-157 amino acids
Related UniRules:	None
Template:	P96618 (ACPS_BACSU); P24224 (ACPS_ECOLI); P0A2W6 (ACPS_STRPN): [Recover all]
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	in ECO57
Plasmid encoded:	None
Comments:	Possible wrong C-terminal sequence in THEMA; not shown in alignment and not used in size range