Accession	MF_00081
Dates	1-JUN-2001 (Created) 7-JUN-2008 (Last updated, Version 17)

Data class

Protein

Predictors

HAMAP; MF_00081; [distribution of match scores in UniProtKB];[seed alignment for MF_00081]

Identifier

HRCA

Protein name

RecName: Full=Heat-inducible transcription repressor hrcA;

Gene name

hrcA

FUNCTION: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity).

SIMILARITY: Belongs to the hrcA family.

Pfam	PF01628; HrcA; 1;
TIGRFAMs	TIGR00331; hrcA; 1;

Transcription, Transcription regulation, Repressor, Stress response.

GO:0016564; Molecular function: transcription repressor activity.
GO:0045892; Biological process: negative regulation of transcription, DNA-dependent.

Size range:	264-398 amino acids
Related UniRules:	None
Template:	P25499 (HRCA_BACSU)
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None
Comments:	Possible wrong starts in a number of sequences. See: MEDLINE=20023017; PubMed=10555317; Ahmad S., Selvapandiyan A., Bhatnagar R.K.; "A protein-based phylogenetic tree for gram-positive bacteria derived from hrcA, a unique heat-shock regulatory gene."; Int. J. Syst. Bacteriol. 49:1387-1394(1999).