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HAMAP annotation rule: MF_00080

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General rule information

Accession MF_00080
Dates 1-JUN-2001 (Created)
16-JUN-2008 (Last updated, Version 24)
Data class Protein
Predictors HAMAP; MF_00080; [distribution of match scores in UniProtKB];[seed alignment for MF_00080]


Propagated annotation

Identifier, protein and gene names

case not <OG:Chloroplast>
Identifier IF3
Protein name
RecName: Full=Translation initiation factor IF-3;
end case


case <OG:Chloroplast>
Identifier IF3C
Protein name
RecName: Full=Translation initiation factor IF-3, chloroplastic;
end case

Gene name infC
Comments
FUNCTION: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity).
SUBUNIT: Monomer (By similarity).

case not <OG:Chloroplast>
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
end case


case <OG:Chloroplast>
SUBCELLULAR LOCATION: Plastid, chloroplast.
end case

SIMILARITY: Belongs to the IF-3 family.
Cross-references
Pfam PF00707; IF3; 1;
TIGRFAMs TIGR00168; infC; 1;
PROSITE PS00938; IF3; 1;
Keywords

case not <OG:Chloroplast>
Cytoplasm.
end case

Initiation factor, Protein biosynthesis.
Gene Ontology
GO:0003743; Molecular function: translation initiation factor activity.
GO:0006413; Biological process: translational initiation.

case not <OG:Chloroplast>
GO:0005737; Cellular component: cytoplasm.
end case


case <OG:Chloroplast>
GO:0009507; Cellular component: chloroplast.
end case



Additional information

Size range: 163-247 amino acids
Related UniRules: None
Template: P03000 (IF3_BACST); P0A707 (IF3_ECOLI); P48516 (IF3_MYXXA); Q9ACJ8 (IF3_THET2): [Recover all]
Scope: Bacteria
Plastid
Fusion: Nter: None; Cter: None
Duplicate: None
Plasmid encoded: None
Comments: Divergent second copy in ANASP, not shown in alignment

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UniProtKB rule member sequences



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