Accession	MF_00075
Dates	1-JUN-2001 (Created) 16-JUN-2008 (Last updated, Version 28)

Data class

Protein

Predictors

HAMAP; MF_00075; [distribution of match scores in UniProtKB];[seed alignment for MF_00075]

Identifier

IF1

Protein name

RecName: Full=Translation initiation factor IF-1;

Identifier

IF1C

Protein name

RecName: Full=Translation initiation factor IF-1, chloroplastic;

Gene name

infA

FUNCTION: No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SUBCELLULAR LOCATION: Plastid, chloroplast.

SIMILARITY: Belongs to the IF-1 family.

SIMILARITY: Contains 1 S1-like domain.

Pfam	PF00575; S1; 1;
TIGRFAMs	TIGR00008; infA; 1;
PROSITE	PS50832; S1_IF1_TYPE; 1; trigger=PRU00181;

Cytoplasm.

Initiation factor, Protein biosynthesis.

Phosphoprotein.

GO:0003723; Molecular function: RNA binding.
GO:0003743; Molecular function: translation initiation factor activity.
GO:0006413; Biological process: translational initiation.

GO:0005737; Cellular component: cytoplasm.

GO:0009507; Cellular component: chloroplast.

From: IF1_BACSU (P20458)
Key		From		To		Description		Condition		FTGroup
MOD_RES		60		60		Phosphotyrosine (By similarity)		Y

Size range:	70-113 amino acids
Related UniRules:	None
Template:	P69222 (IF1_ECOLI)
Scope:	Bacteria Plastid
Fusion:	Nter: None; Cter: None
Duplicate:	in ACIAC, ACISJ, AZOSB, AZOSE, BORA1, BORBR, BORPA, BORPE, BURCA, BURCH, BURCM, BURMA, BURP0, BURP1, BURP6, BURPS, BURS3, BURVG, BURXL, CHRVO, DECAR, DESDG, DESVH, DESVV, LEPBL, METFK, NOVAD, POLSJ, POLSQ, RALEJ, RALME, RALSO, STRAW, SYMTH, THIDA
Plasmid encoded:	in RALME, SILST
Comments:	Possible wrong start in MYCSP Pseudogene in the plastid genome in most rosids (including ARATH), and Solanaceae (including TOBAC). MEDLINE=21149877; PubMed=11251102; DOI=10.1105/tpc.13.3.645; Millen R.S., Olmstead R.G., Adams K.L., Palmer J.D., Lao N.T., Heggie L., Kavanagh T.A., Hibberd J.M., Gray J.C., Morden C.W., Calie P.J., Jermiin L.S., Wolfe K.H.; "Many parallel losses of infA from chloroplast DNA during angiosperm evolution with multiple independent transfers to the nucleus."; Plant Cell 13:645-658(2001).