Accession	MF_00063
Dates	1-JUN-2001 (Created) 7-JUN-2008 (Last updated, Version 25)

Data class

Protein

Predictors

HAMAP; MF_00063; [distribution of match scores in UniProtKB];[seed alignment for MF_00063]

Identifier

CYSH

Protein name

RecName: Full=Phosphoadenosine phosphosulfate reductase; EC=1.8.4.8; AltName: Full=PAPS reductase, thioredoxin dependent; AltName: Full=PAdoPS reductase; AltName: Full=3'-phosphoadenylylsulfate reductase; AltName: Full=PAPS sulfotransferase;

Gene name

cysH

FUNCTION: Reduction of activated sulfate into sulfite (By similarity).

CATALYTIC ACTIVITY: Adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenylyl sulfate + thioredoxin.

PATHWAY: Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 3/3.

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the PAPS reductase family. CysH subfamily.

Pfam	PF01507; PAPS_reduct; 1;
TIGRFAMs	TIGR00434; cysH; 1;

Cytoplasm, Oxidoreductase.

GO:0004604; Molecular function: phosphoadenylyl-sulfate reductase (thioredoxin) activity.
GO:0019379; Biological process: sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin).
GO:0005737; Cellular component: cytoplasm.

Size range:	226-267 amino acids
Related UniRules:	None
Template:	P17854 (CYSH_ECOLI)
Scope:	Bacteria
Fusion:	Nter: None; Cter: None
Duplicate:	in BACSU
Plasmid encoded:	None