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HAMAP annotation rule: MF_00050

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General rule information

Accession MF_00050
Dates 1-JUN-2001 (Created)
4-MAR-2009 (Last updated, Version 29)
Data class Protein
Predictors HAMAP; MF_00050; [distribution of match scores in UniProtKB];[seed alignment for MF_00050]


Propagated annotation

Identifier, protein and gene names

case <OC:Bacteria>
Identifier EFTS
Protein name
RecName: Full=Elongation factor Ts;
Short=EF-Ts;
Gene name tsf

else case <OG:Chloroplast>
Identifier EFTS
Protein name
RecName: Full=Elongation factor Ts, chloroplastic;
Short=EF-Ts;
Gene name tsf
end case

Comments
FUNCTION: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity).

case not <OG:Chloroplast>
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
end case


case <OG:Chloroplast>
SUBCELLULAR LOCATION: Plastid, chloroplast.
end case

SIMILARITY: Belongs to the EF-Ts family.
Cross-references
Pfam PF00889; EF_TS; 1;
PF00627; UBA; 1;
TIGRFAMs TIGR00116; tsf; 1;
PROSITE PS01126; EF_TS_1; 1;
PS01127; EF_TS_2; 1;
Keywords

case not <OG:Chloroplast>
Cytoplasm.
end case

Elongation factor, Protein biosynthesis.
Gene Ontology
GO:0003746; Molecular function: translation elongation factor activity.
GO:0006414; Biological process: translational elongation.

case not <OG:Chloroplast>
GO:0005737; Cellular component: cytoplasm.
end case


case <OG:Chloroplast>
GO:0009507; Cellular component: chloroplast.
end case

Features

case <OC:Bacteria>
From: EFTS_ECOLI (P0A6P1)
Key     From     To       Description   Condition   FTGroup
REGION     80     83       Involved in Mg(2+) ion dislocation from EF-Tu (By similarity)   [TS]-[DE]-F-[LV]  
end case



Additional information

Size range: 196-357 amino acids
Related UniRules: None
Template: P0A6P1 (EFTS_ECOLI); P43895 (EFTS_THET8): [Recover all]
Scope: Bacteria
Plastid
Fusion: Nter: None; Cter: None
Duplicate: None
Plasmid encoded: None

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UniProtKB rule member sequences



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