Accession	MF_00044
Dates	1-JUN-2001 (Created) 7-JUN-2008 (Last updated, Version 26)

Data class

Protein

Predictors

HAMAP; MF_00044_B; [distribution of match scores in UniProtKB];[seed alignment for MF_00044_B]

Predictors

HAMAP; MF_00044_A; [distribution of match scores in UniProtKB];[seed alignment for MF_00044_A]

Identifier

SYD

Protein name

RecName: Full=Aspartyl-tRNA synthetase; EC=6.1.1.12; AltName: Full=Aspartate--tRNA ligase; Short=AspRS;

Gene name

aspS

CATALYTIC ACTIVITY: ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp).

COFACTOR: Binds 3 magnesium ions per subunit (By similarity).

SUBUNIT: Homodimer (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.

Pfam	PF00152; tRNA-synt_2; 1;
PRINTS	PR01042; TRNASYNTHASP; 1;
TIGRFAMs	TIGR00458; aspS_arch; 1; TIGR00459; aspS_bact; 1;
PROSITE	PS50862; AA_TRNA_LIGASE_II; 1;

Cytoplasm, Aminoacyl-tRNA synthetase, Protein biosynthesis, Ligase, ATP-binding, Nucleotide-binding.

Magnesium, Metal-binding.

GO:0004815; Molecular function: aspartate-tRNA ligase activity.
GO:0005524; Molecular function: ATP binding.

GO:0000287; Molecular function: magnesium ion binding.

GO:0006422; Biological process: aspartyl-tRNA aminoacylation.
GO:0005737; Cellular component: cytoplasm.

From: SYD_PYRKO (Q52428)
Key		From		To		Description		Condition		FTGroup
METAL		361		361		Magnesium 2 (By similarity)		E
METAL		361		361		Magnesium 3 (By similarity)		E
METAL		364		364		Magnesium 2 (By similarity)		[ST]

Size range:

550-629 amino acids

Size range:

423-444 amino acids

Related UniRules:	MF_00534 (SYN)
Template:	P21889 (SYD_ECOLI); P36419 (SYD_THETH); Q52428 (SYD_PYRKO): [Recover all]
Scope:	Bacteria Archaea
Fusion:	Nter: <Unknown>; Cter: None
Duplicate:	in STRMU, SYNAS
Plasmid encoded:	None
Comments:	Possible wrong start site in TREPA. Unknown N-terminal domain in MAGMM