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HAMAP annotation rule: MF_01954

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Accession MF_01954
Dates 10-APR-2006 (Created)
25-NOV-2009 (Last updated, Version 15)
Data class Protein
Names Urease_beta



Identifier URE2
Protein name
RecName: Full=Urease subunit beta;
EC=3.5.1.5;
AltName: Full=Urea amidohydrolase subunit beta;
Gene name ureB
CATALYTIC ACTIVITY: Urea + H(2)O = CO(2) + 2 NH(3).
PATHWAY: Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1.
SUBUNIT: Heterotrimer of ureA (gamma), ureB (beta) and ureC (alpha) subunits. Three heterotrimers associate to form the active enzyme (By similarity).
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the urease beta subunit family.
Pfam PF00699; Urease_beta; 1;
TIGRFAMs TIGR00192; urease_beta; 1;
GO:0009039; Molecular function: urease activity.
GO:0005737; Cellular component: cytoplasm.



Size range: 101-164 amino acids
Related UniRules: MF_01955 (URE23 (supersedes the current rule))
Template: P41021 (URE2_BACPA); P18315 (URE2_KLEAE): [Recover all]
Scope: Bacteria
Archaea; Halobacteria
Fusion: Nter: None; Cter: None
Duplicate: in BRUA2, BRUAB, BRUME, BRUSU
Plasmid encoded: in CLOPE, ECOLX, HALMA
Comments: Fused with the urease gamma subunit in a number of bacterial species and in SULTO

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