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HAMAP annotation rule: MF_01810

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Accession MF_01810
Dates 17-NOV-2003 (Created)
25-NOV-2009 (Last updated, Version 22)
Data class Protein
Names OxaA_type1



Identifier OXAA

case <Property:Membrane=1>
Protein name
RecName: Full=Membrane protein oxaA;

else case <Property:Membrane=2>
Protein name
RecName: Full=Inner membrane protein oxaA;
end case

Gene name oxaA
FUNCTION: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and independently of the Sec translocase complex (By similarity).
SUBUNIT: Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration (By similarity).

case <Property:Membrane=1>
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (By similarity).

else case <Property:Membrane=2>
SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein (By similarity).
end case

SIMILARITY: Belongs to the OXA1/oxaA family. Type 1 subfamily.
Pfam PF02096; 60KD_IMP; 1;
PRINTS PR00701; 60KDINNERMP; 1;
General Transmembrane; -; 2-7; trigger=Yes;

case <Property:Membrane=2>
end case

GO:0005886; Cellular component: plasma membrane.



Size range: 310-795 amino acids
Related UniRules: MF_01811 (OXAA (supersedes the current rule))
Template: P25714 (OXAA_ECOLI)
Scope: Bacteria
Fusion: Nter: <PDZ/DHR>; Cter: None
Duplicate: None
Plasmid encoded: None
Comments: N-terminal PDZ/DHR fused in RHOBA. In most Firmicutes (MF_01811), this protein is much shorter and contains a signal peptide with a site for a lipid attachment in the N-terminus part.

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