ExPASy Proteomics Server

Accession	MF_01707
Dates	11-OCT-2004 (Created) 25-NOV-2009 (Last updated, Version 13)

Data class

Protein

Predictors

PROSITE; PS51243; [distribution of match scores in UniProtKB]

Names

ABC_ATPase_CcmA

Identifier

CCMA

Protein name

RecName: Full=Cytochrome c biogenesis ATP-binding export protein ccmA; EC=3.6.3.41; AltName: Full=Heme exporter protein A;

Gene name

ccmA

FUNCTION: Part of the ABC transporter complex ccmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity).

CATALYTIC ACTIVITY: ATP + H(2)O + heme(In) = ADP + phosphate + heme(Out).

SUBUNIT: The complex is composed of two ATP-binding proteins (ccmA) and two transmembrane proteins (ccmB) (Probable).

SIMILARITY: Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.

SUBCELLULAR LOCATION: Cell inner membrane; Peripheral membrane protein (By similarity).

SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein (By similarity).

SUBCELLULAR LOCATION: Mitochondrion membrane; Peripheral membrane protein (By similarity).

Pfam	PF00005; ABC_tran; 1;
TIGRFAMs	TIGR01189; ccmA; 1;
PROSITE	PS00211; ABC_TRANSPORTER_1; 1; PS50893; ABC_TRANSPORTER_2; 1; trigger=PRU00434;

GO:0006810; Biological process: transport.
GO:0005215; Molecular function: transporter activity.

GO:0005886; Cellular component: plasma membrane.

GO:0031966; Cellular component: mitochondrial membrane.

Transport, Hydrolase, Cytochrome c-type biogenesis.

Size range:	192-345 amino acids
Related UniRules:	PRU01700
Template:	P33931 (CCMA_ECOLI)
Scope:	Bacteria; Deinococci Bacteria; Proteobacteria Eukaryota; Arabidopsis Mitochondrion
Fusion:	Nter: None; Cter: ccmE
Duplicate:	None
Plasmid encoded:	None