ExPASy Proteomics Server

Accession	MF_01632
Dates	6-JUN-2006 (Created) 25-NOV-2009 (Last updated, Version 16)

Data class

Protein

Predictors

HAMAP; MF_01632; [distribution of match scores in UniProtKB];[seed alignment for MF_01632]

Names

UbiC

Identifier

UBIC

Protein name

RecName: Full=Chorismate--pyruvate lyase; Short=CL; Short=CPL; EC=4.1.3.40;

Protein name

RecName: Full=Probable chorismate--pyruvate lyase; Short=CL; Short=CPL; EC=4.1.3.40;

Gene name

ubiC

FUNCTION: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity).

CATALYTIC ACTIVITY: Chorismate = 4-hydroxybenzoate + pyruvate.

PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.

SUBUNIT: Monomer (By similarity).

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

SIMILARITY: Belongs to the ubiC family.

Pfam	PF04345; Chor_lyase; 1;

Cytoplasm, Lyase, Pyruvate, Ubiquinone biosynthesis.

GO:0008813; Molecular function: chorismate lyase activity.
GO:0006744; Biological process: ubiquinone biosynthetic process.
GO:0042866; Biological process: pyruvate biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

From: UBIC_ECOLI (P26602)
Key		From		To		Description		Condition		FTGroup
BINDING		35		35		Substrate; via amide nitrogen (By similarity)		M
BINDING		77		77		Substrate (By similarity)		R
BINDING		115		115		Substrate; via amide nitrogen (By similarity)		[LI]

Size range:	162-227 amino acids
Related UniRules:	None
Template:	P26602 (UBIC_ECOLI)
Scope:	Bacteria; Proteobacteria
Fusion:	Nter: None; Cter: None
Duplicate:	in BURP1, PSEE4, PSEPF
Plasmid encoded:	None