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HAMAP annotation rule: MF_01574

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General rule information

Accession MF_01574
Dates 2-NOV-2006 (Created)
25-NOV-2009 (Last updated, Version 6)
Data class Protein
Predictors HAMAP; MF_01574; [distribution of match scores in UniProtKB];[seed alignment for MF_01574]
Names LacG


Propagated annotation

Identifier, protein and gene names
Identifier LACG
Protein name
RecName: Full=6-phospho-beta-galactosidase;
EC=3.2.1.85;
AltName: Full=Beta-D-phosphogalactoside galactohydrolase;
Short=PGALase;
AltName: Full=P-beta-Gal;
Short=PBG;
Gene name lacG
Comments
CATALYTIC ACTIVITY: A 6-phospho-beta-D-galactoside + H(2)O = 6-phospho-D-galactose + an alcohol.
PATHWAY: Carbohydrate metabolism; lactose degradation; D-galactose 6-phosphate and beta-D-glucose from lactose 6-phosphate: step 1/1.
SIMILARITY: Belongs to the glycosyl hydrolase 1 family.
Cross-references
PROSITE PS00572; GLYCOSYL_HYDROL_F1_1; 1;
PS00653; GLYCOSYL_HYDROL_F1_2; 1;
Pfam PF00232; Glyco_hydro_1; 1;
PRINTS PR00131; GLHYDRLASE1; 1;
TIGRFAMs TIGR01233; lacG; 1;
Keywords
Glycosidase, Hydrolase.
Gene Ontology
GO:0015925; Molecular function: galactosidase activity.
GO:0005990; Biological process: lactose catabolic process.
Features
From: LACG_LACLA (P11546)
Key     From     To       Description   Condition   FTGroup
ACT_SITE     160     160       Proton donor (By similarity)   E  
ACT_SITE     375     375       Nucleophile (By similarity)   E  


Additional information

Size range: 468-474 amino acids
Related UniRules: None
Template: P11546 (LACG_LACLA); P11175 (LACG_STAAU): [Recover all]
Scope: Bacteria; Firmicutes
Fusion: Nter: None; Cter: None
Duplicate: in STRPN, STRR6
Plasmid encoded: in LACLA

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UniProtKB rule member sequences