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HAMAP annotation rule: MF_01545

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General rule information

Accession MF_01545
Dates 4-NOV-2005 (Created)
25-NOV-2009 (Last updated, Version 14)
Data class Protein
Predictors HAMAP; MF_01545; [distribution of match scores in UniProtKB];[seed alignment for MF_01545]
Names AaeB


Propagated annotation

Identifier, protein and gene names
Identifier AAEB
Protein name
RecName: Full=p-hydroxybenzoic acid efflux pump subunit aaeB;
Short=pHBA efflux pump protein B;
Gene name aaeB
Comments
FUNCTION: Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell (By similarity).

case <Property:Membrane=1>
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (By similarity).

else case <Property:Membrane=2>
SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein (By similarity).
end case


case <OC:Escherichia>
INDUCTION: Positively coregulated with aaeA and aaeX by aaeR (By similarity).
end case

MISCELLANEOUS: Both aaeB and aaeA are required for the function of the efflux system (By similarity).
SIMILARITY: Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
Cross-references
Pfam PF04632; FUSC; 1;
General Transmembrane; -; 11; trigger=Yes;
Keywords
Cell membrane.

case <Property:Membrane=2>
Cell inner membrane.
end case

Membrane, Transmembrane, Transport.
Gene Ontology
GO:0006810; Biological process: transport.
GO:0005886; Cellular component: plasma membrane.


Additional information

Size range: 651-662 amino acids
Related UniRules: None
Template: P46481 (AAEB_ECOLI)
Scope: Bacteria; Enterobacteriaceae
Fusion: Nter: None; Cter: None
Duplicate: None
Plasmid encoded: None

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UniProtKB rule member sequences