ExPASy Proteomics Server

Accession	MF_01443
Dates	12-JUL-2007 (Created) 25-NOV-2009 (Last updated, Version 5)

Data class

Protein

Predictors

HAMAP; MF_01443; [distribution of match scores in UniProtKB];[seed alignment for MF_01443]

Names

PrpE

Identifier

PRPE

Protein name

RecName: Full=Bis(5'-nucleosyl)-tetraphosphatase prpE [asymmetrical]; EC=3.6.1.17; AltName: Full=Ap4A hydrolase; AltName: Full=Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase; Short=Diadenosine tetraphosphatase;

Gene name

prpE

FUNCTION: Asymmetrically hydrolyzes Ap4p to yield AMP and ATP (By similarity).

CATALYTIC ACTIVITY: P(1),P(4)-bis(5'-guanosyl) tetraphosphate + H(2)O = GTP + GMP.

COFACTOR: Nickel (By similarity).

SIMILARITY: Belongs to the prpE family.

Pfam	PF00149; Metallophos; 1;
PRINTS	PR00114; STPHPHTASE; 1;

GTP-binding, Hydrolase, Nickel, Nucleotide-binding.

GO:0004081; Molecular function: bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity.
GO:0016151; Molecular function: nickel ion binding.

Size range:	244-250 amino acids
Related UniRules:	None
Template:	O31614 (PRPE_BACSU)
Scope:	Bacteria; Bacillaceae
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None