ExPASy Proteomics Server

Accession	MF_01339
Dates	8-NOV-2005 (Created) 25-NOV-2009 (Last updated, Version 10)

Data class

Protein

Predictors

HAMAP; MF_01339; [distribution of match scores in UniProtKB];[seed alignment for MF_01339]

Names

RuBisCO_L_type2

Identifier

RBL2

Protein name

RecName: Full=Ribulose bisphosphate carboxylase; Short=RuBisCO; EC=4.1.1.39;

Gene name

cbbM

FUNCTION: RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site (By similarity).

CATALYTIC ACTIVITY: 2 3-phospho-D-glycerate + 2 H(+) = D-ribulose 1,5-bisphosphate + CO(2) + H(2)O.

CATALYTIC ACTIVITY: 3-phospho-D-glycerate + 2-phosphoglycolate = D-ribulose 1,5-bisphosphate + O(2).

COFACTOR: Binds 1 magnesium ion per subunit (By similarity).

SUBUNIT: Homodimer (By similarity).

MISCELLANEOUS: The basic functional RuBisCO is composed of a large chain homodimer in a "head-to-tail" conformation. In contrast to form I RuBisCO, the form II RuBisCO are composed solely of large subunits (By similarity).

SIMILARITY: Belongs to the RuBisCO large chain family. Type II subfamily.

PROSITE	PS00157; RUBISCO_LARGE; 1;
Pfam	PF00016; RuBisCO_large; 1; PF02788; RuBisCO_large_N; 1;

Calvin cycle, Carbon dioxide fixation, Lyase.

Magnesium, Metal-binding.

Monooxygenase, Oxidoreductase.

Photosynthesis.

GO:0000287; Molecular function: magnesium ion binding.

GO:0016984; Molecular function: ribulose-bisphosphate carboxylase activity.

From: RBL2_RHORU (P04718)
Key		From		To		Description		Condition		FTGroup
ACT_SITE		166		166		Proton acceptor (By similarity)		K
ACT_SITE		287		287		Proton acceptor (By similarity)		H
METAL		191		191		Magnesium; via carbamate group (By similarity)		K		1
METAL		193		193		Magnesium (By similarity)		D		1
METAL		194		194		Magnesium (By similarity)		E		1
SITE		329		329		Transition state stabilizer (By similarity)		K
BINDING		111		111		Substrate; in homodimeric partner (By similarity)		N
BINDING		168		168		Substrate (By similarity)		K
BINDING		288		288		Substrate (By similarity)		R
BINDING		321		321		Substrate (By similarity)		H
BINDING		368		368		Substrate (By similarity)		S
MOD_RES		191		191		N6-carboxylysine (By similarity)		K

Size range:	458-466 amino acids
Related UniRules:	MF_01133 (RBL); MF_01338 (RBL)
Template:	P04718 (RBL2_RHORU)
Scope:	Bacteria; Rhodopseudomonas Bacteria; Rhodobacterales Bacteria; Rhodospirillales Bacteria; Comamonadaceae Bacteria; Thiomonas Bacteria; Hydrogenophilales Bacteria; Rhodocyclaceae Bacteria; Halothiobacillus Bacteria; Hydrogenovibrio Bacteria; Thiomicrospira
Fusion:	Nter: None; Cter: None
Duplicate:	None
Plasmid encoded:	None