ExPASy Proteomics Server

Accession	MF_01217
Dates	26-JUN-2002 (Created) 25-NOV-2009 (Last updated, Version 27)

Data class

Protein

Predictors

HAMAP; MF_01217; [distribution of match scores in UniProtKB];[seed alignment for MF_01217]

Names

Acyl_carrier

Identifier

ACP

Protein name

RecName: Full=Acyl carrier protein; Short=ACP;

Gene name

acpP

FUNCTION: Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity).

PATHWAY: Lipid metabolism; fatty acid biosynthesis.

SUBCELLULAR LOCATION: Plastid, chloroplast.

SUBCELLULAR LOCATION: Cytoplasm (By similarity).

PTM: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group (By similarity).

SIMILARITY: Contains 1 acyl carrier domain.

Pfam	PF00550; PP-binding; 1;
TIGRFAMs	TIGR00517; acyl_carrier; 1;
PROSITE	PS00012; PHOSPHOPANTETHEINE; 1; PS50075; ACP_DOMAIN; 1;

Cytoplasm.

Lipid synthesis, Fatty acid biosynthesis, Phosphopantetheine.

GO:0000036; Molecular function: acyl carrier activity.
GO:0006633; Biological process: fatty acid biosynthetic process.

GO:0009507; Cellular component: chloroplast.

GO:0005737; Cellular component: cytoplasm.

From: ACP_ECOLI (P0A6A8)
Key		From		To		Description		Condition		FTGroup
MOD_RES		37		37		O-(pantetheine 4'-phosphoryl)serine (By similarity)		S

Size range:	69-95 amino acids
Related UniRules:	None
Template:	P0A6A8 (ACP_ECOLI); P80643 (ACP_BACSU); P20803 (ACP_ANAVA); P94123 (ACP_AZOBR); O54439 (ACP1_PSEAE); Q9RG22 (ACP_RHILE); P19372 (ACP_RHIME); P12784 (ACP_RHOSH); P11830 (ACP_SACEN); P20804 (ACP_SYNY3): [Recover all]
Scope:	Bacteria Plastid
Fusion:	Nter: None; Cter: None
Duplicate:	in CLOAB, PSEAE, RALSO
Plasmid encoded:	in RALSO, SHIDY, SHIFL
Comments:	Longer C-terminal in MYCTU, MYCLE and in the second copy in CLOAB; sequences not shown in alignment and not taken into account in size range. Longer sequence in CYAPA; not shown in alignment and not taken into account in size range.